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Indication -
Cancer
Lactate dehydrogenase (LDH)
Assay formats
Optical methods, automated chemistry analyser if available
Status history
First added in 2019
Changed in 2020
Purpose type
Prognosis, Monitoring
Purpose
To aid in the prognosis and monitoring of haematological malignancies (e.g. lymphoma) and germ cell tumours
NOTE: Also used as a marker for heart disease, liver disease, Pneumocystis infection, thrombotic thrombocytopenic purpura (TTP), and other malignancies
Specimen types
Serum, Plasma
WHO prequalified or recommended products
N/A
WHO supporting documents
WHO classification of tumours of haematopoietic and lymphoid tissues. WHO classification of tumours, revised 4th edition, volume 2.
https://publications.iarc.fr/Book-And-Report-Series/Who-Classification-Of-Tumours/WHO-Classification-Of-Tumours-Of-Haematopoietic-And-Lymphoid-Tissues-2017
WHO classification of tumours of the urinary system and male genital organs. WHO classification of tumours, 4th edition, volume 8.
https://publications.iarc.fr/Book-And-Report-Series/Who-Classification-Of-Tumours/WHO-Classification-Of-Tumours-Of-The-Urinary-System-And-Male-Genital-Organs-2016
WHO classification of tumours of female reproductive organs. WHO classification of tumours, 4th edition, volume 6.
https://publications.iarc.fr/Book-And-Report-Series/Who-Classification-Of-Tumours/WHO-Classification-Of-Tumours-Of-Female-Reproductive-Organs-2014
Codes
ICD11 code:
2D4Y
Summary of SAGE IVD recommendation
General In vitro diagnostics tests are the general core and routine laboratory tests for clinical chemistry, haematology, blood transfusion, microbiology (virology, bacteriology, parasitology and mycology) and histopathology. These tests were selected on the basis of the scientific validity of an analyte, i.e. the association between an analyte and a clinical condition or physiological state; and clinical utility. Many of these tests are required for effective management of patients and have already been described in WHO publications.