Discipline - Clinical chemistry
Ionized calcium
Facility level:
Assay formats
Blood gas analysers, including portable analysers for emergency and critical care
Status history
First added in 2020
Purpose type
Determination of Physiological Status
To measure free (ionized) calcium in situations in which there are changes in the concentrations of certain proteins (such as albumin) and/or changes in physiological status such as acid–base disorders. To diagnose and monitor hypercalcaemia or hypocalcaemia.
Specimen types
Arterial whole blood, Venous whole blood, Capillary whole blood

Summary of SAGE IVD recommendation

General In vitro diagnostics tests are the general core and routine laboratory tests for clinical chemistry, haematology, blood transfusion, microbiology (virology, bacteriology, parasitology and mycology) and histopathology. These tests were selected on the basis of the scientific validity of an analyte, i.e. the association between an analyte and a clinical condition or physiological state; and clinical utility. Many of these tests are required for effective management of patients and have already been described in WHO publications.

Details of submission from 2020

The inclusion of this entry was based on WHO guidelines and technical reports that include recommendations for the appropriate IVDs.